Parthenolide Is Neuroprotective in Rat Experimental Stroke Model: Downregulating NF-κB, Phospho-p38MAPK, and Caspase-1 and Ameliorating BBB Permeability

Inflammatory damage plays an important role in cerebral ischemic pathogenesis and may represent a target for treatment. Parthenolide (PN) has been proved to elicit a wide range of biological activities through its anti-inflammatory action in the treatment of migraine, arthritis, and atherosclerosis....

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Autors principals: Dong, Lipeng, Qiao, Huimin, Zhang, Xiangjian, Zhang, Xiaolin, Wang, Chaohui, Wang, Lina, Cui, Lili, Zhao, Jingru, Xing, Yinxue, Li, Yanhua, Liu, Zongjie, Zhu, Chunhua
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725704/
https://ncbi.nlm.nih.gov/pubmed/23935248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/370804
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