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TCR-dependent and –independent activation underlie liver-specific regulation of NKT cells

The fate of iNKT cells following activation remains controversial and unclear. We systemically examined how iNKT cells are regulated following TCR-dependent and -independent activation with alpha-Galactosylceramide (αGC) or IL-18+IL-12 respectively. Our studies reveal activation by αGC or IL-18+IL-1...

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Detalhes bibliográficos
Main Authors: Subleski, Jeff J., Hall, Veronica L., Wolfe, Thomas B., Scarzello, Anthony J., Weiss, Jonathan M., Chan, Tim, Hodge, Deborah L., Back, Timothy C., Ortaldo, John R., Wiltrout, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725575/
https://ncbi.nlm.nih.gov/pubmed/21148802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001735
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