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NHE8 plays an important role in mucosal protection via its effect on bacterial adhesion

The Na(+)/H(+) exchanger NHE8 is expressed on the apical membrane of intestinal epithelial cells and is particularly abundant in the colon. Our previous study showed that Muc2 expression was significantly reduced in NHE8-knockout (NHE8(−/−)) mice, suggesting that NHE8 plays a role in mucosal protect...

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Autors principals: Liu, Chang, Xu, Hua, Zhang, Bo, Johansson, Malin E. V., Li, Jing, Hansson, Gunnar C., Ghishan, Fayez K.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725519/
https://ncbi.nlm.nih.gov/pubmed/23657568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00101.2013
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