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Identification of α-Adrenergic Receptors in Human Platelets by [(3)H]Dihydroergocryptine Binding

Binding of [(3)H]dihydroergocryptine to platelet lysates appears to have all the characteristics of binding to α-adrenergic receptors. At 25°C binding reaches equilibrium within 20 min and is reversible upon addition of excess phentolamine. Binding is saturable with 183±22 fmol of [(3)H]dihydroergoc...

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Udgivet i:J Clin Invest
Principais autores: Newman, Kurt D., Williams, Lewis T., Bishopric, N. Hahr, Lefkowitz, Robert J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1978
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372550/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/23392/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108950
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