Optimisation of a functional mycobacterial growth-inhibition assay to improve its suitability for infant TB vaccine studies()

The development of vaccines against tuberculosis continues to be hindered by the lack of correlates of protection. Immunity to Mycobacterium tuberculosis (M.tb) infection relies predominantly on cell mediated response, which is routinely measured using a read-out of host cytokine profiles. However,...

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Main Authors: Burl, S., Holder, B.S., Lo, B.K.M., Kampmann, B.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2013
Fag:
Technical Note
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725412/
https://ncbi.nlm.nih.gov/pubmed/23707325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2013.05.006
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