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TASK-2: a K(2P) K(+) channel with complex regulation and diverse physiological functions

TASK-2 (K(2P)5.1) is a two-pore domain K(+) channel belonging to the TALK subgroup of the K(2P) family of proteins. TASK-2 has been shown to be activated by extra- and intracellular alkalinization. Extra- and intracellular pH-sensors reside at arginine 224 and lysine 245 and might affect separate se...

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Bibliographic Details
Main Authors: Cid, L. Pablo, Roa-Rojas, Hugo A., Niemeyer, María I., González, Wendy, Araki, Masatake, Araki, Kimi, Sepúlveda, Francisco V.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725403/
https://ncbi.nlm.nih.gov/pubmed/23908634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2013.00198
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