Bactofection of lung epithelial cells in vitro and in vivo using a genetically modified Escherichia coli

Bacteria-mediated gene transfer (‘bactofection’) has emerged as an alternative approach for genetic vaccination and gene therapy. Here, we assessed bactofection of airway epithelial cells in vitro and in vivo using an attenuated Escherichia coli genetically engineered to invade non-phagocytic cells....

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Autori principali: Larsen, MDB, Griesenbach, U, Goussard, S, Gruenert, DC, Geddes, DM, Scheule, RK, Cheng, SH, Courvalin, P, Grillot-Courvalin, C, Alton, EWFW
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725396/
https://ncbi.nlm.nih.gov/pubmed/18317498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gt.3303090
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