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Bactofection of lung epithelial cells in vitro and in vivo using a genetically modified Escherichia coli

Bacteria-mediated gene transfer (‘bactofection’) has emerged as an alternative approach for genetic vaccination and gene therapy. Here, we assessed bactofection of airway epithelial cells in vitro and in vivo using an attenuated Escherichia coli genetically engineered to invade non-phagocytic cells....

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Hlavní autoři: Larsen, MDB, Griesenbach, U, Goussard, S, Gruenert, DC, Geddes, DM, Scheule, RK, Cheng, SH, Courvalin, P, Grillot-Courvalin, C, Alton, EWFW
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725396/
https://ncbi.nlm.nih.gov/pubmed/18317498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gt.3303090
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