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Interleukin-1 receptor mediates the interplay between CD4(+) T cells and ocular resident cells to promote keratinizing squamous metaplasia in Sjögren’s syndrome

Keratinizing squamous metaplasia (SQM) of the ocular mucosal epithelium is a blinding corneal disease characterized by the loss of conjunctival goblet cells (GCs), pathological ocular surface keratinization and tissue recruitment of immune cells. Using the autoimmune regulator (Aire)-deficient mouse...

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Hlavní autoři: Chen, Ying-Ting, Lazarev, Stanislav, Bahrami, Ahmad F, Noble, Lisa B, Chen, Feeling YT, Zhou, Delu, Gallup, Marianne, Yadav, Mahesh, McNamara, Nancy A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725338/
https://ncbi.nlm.nih.gov/pubmed/22231738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2011.189
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