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Phosphinic Acid-Based Inhibitors of Tubulin Polyglutamylases
Tubulin is subject to a reversible post-translational modification involving polyglutamylation and deglutamylation of glutamate residues in its C-terminal tail. This process plays key roles in regulating the function of microtubule associated proteins, neuronal development, and metastatic progressio...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3725182/ https://ncbi.nlm.nih.gov/pubmed/23777780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.05.069 |
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