A gene expression profile indicative of early stage HER2 targeted therapy response

BACKGROUND: Efficacious application of HER2-targetting agents requires the identification of novel predictive biomarkers. Lapatinib, afatinib and neratinib are tyrosine kinase inhibitors (TKIs) of HER2 and EGFR growth factor receptors. A panel of breast cancer cell lines was treated with these agent...

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Bibliografiska uppgifter
Huvudupphovsmän: O’Neill, Fiona, Madden, Stephen F, Clynes, Martin, Crown, John, Doolan, Padraig, Aherne, Sinéad T, O’Connor, Robert
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725168/
https://ncbi.nlm.nih.gov/pubmed/23816254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-69
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