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Effect of Proteolytic Enzymes on the Binding of Cobalamin to R Protein and Intrinsic Factor

Cobalamin (Cbl; vitamin B(12)) malabsorption in pancreatic insufficiency can be partially corrected by bicarbonate and completely corrected by pancreatic proteases but the mechanisms involved are unknown. Because saliva contains enough R-type Cbl-binding protein (R protein) to bind all of the dietar...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Allen, Robert H., Seetharam, Bellur, Podell, Elaine, Alpers, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372512/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/22556/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108924
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