PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma

Diffuse large B-cell lymphoma (DLBCL) represents a heterogeneous diagnostic category with distinct molecular subtypes that can be defined by gene expression profiling. However, even within these defined subtypes, heterogeneity prevails. To further elucidate the pathogenesis of these entities, we det...

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Detalhes bibliográficos
Main Authors: Pfeifer, Matthias, Grau, Michael, Lenze, Dido, Wenzel, Sören-Sebastian, Wolf, Annette, Wollert-Wulf, Brigitte, Dietze, Kerstin, Nogai, Hendrik, Storek, Benjamin, Madle, Hannelore, Dörken, Bernd, Janz, Martin, Dirnhofer, Stephan, Lenz, Peter, Hummel, Michael, Tzankov, Alexandar, Lenz, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725065/
https://ncbi.nlm.nih.gov/pubmed/23840064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305656110
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