Gastric Expression of Plasminogen Activator Inhibitor (PAI)-1 Is Associated with Hyperphagia and Obesity in Mice

The adipokine plasminogen activator inhibitor (PAI)-1 is increased in plasma of obese individuals and exhibits increased expression in the stomachs of individuals infected with Helicobacter. To investigate the relevance of gastric PAI-1, we used 1.1 kb of the H(+)/K(+)β subunit promoter to overexpre...

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Bibliographic Details
Main Authors: Kenny, Susan, Gamble, Joanne, Lyons, Suzanne, Vlatković, Nikolina, Dimaline, Rod, Varro, Andrea, Dockray, Graham J.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2013
Subjects:
Energy Balance-Obesity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724960/
https://ncbi.nlm.nih.gov/pubmed/23254194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1913
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