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Trivalent Combination Vaccine Induces Broad Heterologous Immune Responses to Norovirus and Rotavirus in Mice

Rotavirus (RV) and norovirus (NoV) are the two major causes of viral gastroenteritis (GE) in children worldwide. We have developed an injectable vaccine design to prevent infection or GE induced with these enteric viruses. The trivalent combination vaccine consists of NoV capsid (VP1) derived virus-...

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Библиографические подробности
Главные авторы: Tamminen, Kirsi, Lappalainen, Suvi, Huhti, Leena, Vesikari, Timo, Blazevic, Vesna
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724941/
https://ncbi.nlm.nih.gov/pubmed/23922988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070409
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