Variations of the ataxia telangiectasia mutated gene in patients with chronic lymphocytic leukemia lack substantial impact on progression-free survival and overall survival: a Cancer and Leukemia Group B study

The impact of mutation of the ATM (ataxia telangiectasia mutated) gene in chronic lymphocytic leukemia (CLL) treatment outcome has not been examined. We studied ATM mutations in 73 patients treated with fludarabine and rituximab. ATM gene mutation analysis was performed using temperature gradient ca...

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Detalhes bibliográficos
Main Authors: Lozanski, Gerard, Ruppert, Amy S., Heerema, Nyla A., Lozanski, Arletta, Lucas, David M., Gordon, Amber, Gribben, John G., Morrison, Vicki A., Rai, Kanti M., Marcucci, Guido, Larson, Richard A., Byrd, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724930/
https://ncbi.nlm.nih.gov/pubmed/22369572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2012.668683
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