Dimerization of the Glucan Phosphatase Laforin Requires the Participation of Cysteine 329

Laforin, encoded by a gene that is mutated in Lafora Disease (LD, OMIM 254780), is a modular protein composed of a carbohydrate-binding module and a dual-specificity phosphatase domain. Laforin is the founding member of the glucan-phosphatase family and regulates the levels of phosphate present in g...

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Главные авторы: Sánchez-Martín, Pablo, Raththagala, Madushi, Bridges, Travis M., Husodo, Satrio, Gentry, Matthew S., Sanz, Pascual, Romá-Mateo, Carlos
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724922/
https://ncbi.nlm.nih.gov/pubmed/23922729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069523
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