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Blood Viscosity and the Expression of Inflammatory and Adhesion Markers in Homozygous Sickle Cell Disease Subjects with Chronic Leg Ulcers

OBJECTIVE: To determine differences in TNF-α, IL-1β, IL-10, sICAM-1 concentrations, leg hypoxia and whole blood viscosity (WBV) at shear rates of 46 sec(-1) and 230 sec(-1) in persons with homozygous S sickle cell disease (SCD) with and without chronic leg ulceration and in AA genotype controls. DES...

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Detalhes bibliográficos
Main Authors: Bowers, Andre S., Reid, Harvey L., Greenidge, Andre, Landis, Clive, Reid, Marvin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724890/
https://ncbi.nlm.nih.gov/pubmed/23922670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068929
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