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Development of a Nuclear Morphometric Signature for Prostate Cancer Risk in Negative Biopsies

BACKGROUND: Our objective was to develop and validate a multi-feature nuclear score based on image analysis of direct DNA staining, and to test its association with field effects and subsequent detection of prostate cancer (PCa) in benign biopsies. METHODS: Tissue sections from 39 prostatectomies we...

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Detalhes bibliográficos
Main Authors: Gann, Peter H., Deaton, Ryan, Amatya, Anup, Mohnani, Mahesh, Rueter, Erika Enk, Yang, Yirong, Ananthanarayanan, Viju
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724855/
https://ncbi.nlm.nih.gov/pubmed/23922715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069457
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