Intratumoral localization and activity of 17β-hydroxysteroid dehydrogenase type 1 in non-small cell lung cancer: a potent prognostic factor

BACKGROUND: Estrogens were recently demonstrated to be synthesized in non-small cell lung carcinomas (NSCLCs) via aromatase activity and aromatase inhibitor (AI) did suppressed estrogen receptor (ER) positive NSCLC growth. However, other enzymes involved in intratumoral production and metabolism of...

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Detalhes bibliográficos
Main Authors: Verma, Mohit K, Miki, Yasuhiro, Abe, Keiko, Suzuki, Takashi, Niikawa, Hiromichi, Suzuki, Satoshi, Kondo, Takashi, Sasano, Hironobu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724709/
https://ncbi.nlm.nih.gov/pubmed/23837683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-167
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