Crystal Structures of Copper-depleted and Copper-bound Fungal Pro-tyrosinase: INSIGHTS INTO ENDOGENOUS CYSTEINE-DEPENDENT COPPER INCORPORATION

Tyrosinase, a dinuclear copper monooxygenase/oxidase, plays a crucial role in the melanin pigment biosynthesis. The structure and functions of tyrosinase have so far been studied extensively, but the post-translational maturation process from the pro-form to the active form has been less explored. I...

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Detalhes bibliográficos
Main Authors: Fujieda, Nobutaka, Yabuta, Shintaro, Ikeda, Takuya, Oyama, Takuji, Muraki, Norifumi, Kurisu, Genji, Itoh, Shinobu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724665/
https://ncbi.nlm.nih.gov/pubmed/23749993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.477612
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