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Ketogenic Diet Treatment Abolishes Seizure Periodicity and Improves Diurnal Rhythmicity in Epileptic Kcna1-null Mice

INTRODUCTION: Seizures are known to perturb circadian rhythms in humans as well as in animal models of epilepsy. However, it is unknown whether treatment of the underlying epilepsy restores normal biological rhythms. We asked whether: (1) seizure activity is characterized by diurnal rhythmicity; (2)...

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Main Authors: Fenoglio-Simeone, Kristina A., Wilke, Julianne C., Milligan, Heather L., Allen, Charles N., Rho, Jong M., Maganti, Rama K.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724531/
https://ncbi.nlm.nih.gov/pubmed/19490051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2009.02163.x
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