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Effects of hyperglycemia and oxidative stress on the glutamate transporters GLAST and system x(c)(−) in mouse retinal Müller glial cells

Elevated glutamate levels have been reported in humans with diabetic retinopathy. Retinal Müller glial cells regulate glutamate levels via the GLAST transporter and system x(c)(−) (cystine-glutamate exchanger). This study investigated whether transporter function, gene and/or protein expression is a...

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Bibliographic Details
Main Authors: Mysona, Barbara, Dun, Ying, Duplantier, Jennifer, Ganapathy, Vadivel, Smith, Sylvia B.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724468/
https://ncbi.nlm.nih.gov/pubmed/19156441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-008-0742-1
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