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Cutting Edge: Low-Affinity, Smith Antigen-Specific B Cells Are Tolerized by Dendritic Cells and Macrophages()

Polyclonal B cell activation promotes immunity without the loss of tolerance. Our data show that during activation of the innate immune system, B cell tolerance to Smith Ag Sm is maintained by dendritic cells (DCs) and macrophages (MΦ). TLR4-activated myeloid DCs and MΦ, but not plasmacytoid or lymp...

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Autors principals: Kilmon, Michelle A., Rutan, Jennifer A., Clarke, Stephen H., Vilen, Barbara J.
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724409/
https://ncbi.nlm.nih.gov/pubmed/15972629
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