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Two-photon imaging of multiple fluorescent proteins by phase-shaping and linear unmixing with a single broadband laser

Imaging multiple fluorescent proteins (FPs) by two-photon microscopy has numerous applications for studying biological processes in thick and live samples. Here we demonstrate a setup utilizing a single broadband laser and a phase-only pulse-shaper to achieve imaging of three FPs (mAmetrine, TagRFPt...

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Bibliografische gegevens
Hoofdauteurs: Brenner, Meredith H., Cai, Dawen, Swanson, Joel A., Ogilvie, Jennifer P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Optical Society of America 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724397/
https://ncbi.nlm.nih.gov/pubmed/23938572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/OE.21.017256
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