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A Role for Prostaglandin E in Defective Insulin Secretion and Carbohydrate Intolerance in Diabetes Mellitus

Prostaglandin E(2) (PGE(2)) infusion in normal humans inhibited acute insulin responses to a glucose (5 g i.v.) pulse (response before PGE(2) = 593 ± 104%; during PGE(2) = 312±55%; mean±SE, mean change 3-5 min insulin,% basal, P < 0.005). This effect was associated with a decrease in glucose disa...

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Bibliographic Details
Main Authors: Robertson, R. Paul, Chen, Mei
Format: Artigo
Language:Inglês
Published: 1977
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC372420/
https://ncbi.nlm.nih.gov/pubmed/330566
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