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O-GlcNAcylation and p50/p105 binding of c-Rel are dynamically regulated by LPS and glucosamine in BV2 microglia cells

BACKGROUND AND PURPOSE: Previously, we demonstrated that glucosamine (GlcN) exerts a suppressive effect on LPS-induced inducible NOS (iNOS) through the inhibition of NF-κB activation in BV2 mouse microglial cells. The purpose of the present study was to examine the mechanisms by which GlcN inhibits...

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Detalhes bibliográficos
Main Authors: Hwang, So-Young, Hwang, Ji-Sun, Kim, Song-Yi, Han, Inn-Oc
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724111/
https://ncbi.nlm.nih.gov/pubmed/23646894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12223
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