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Molecular mechanisms underlying the anti-proliferative and anti-migratory effects of folate on homocysteinechallenged rat aortic smooth muscle cells

BACKGROUND AND PURPOSE: Homocysteine is an intermediate product formed during the metabolism of methionine, and is increased in cells with folate deficiency. Patients with hyperhomocysteinemia tend to develop cardiovascular disease. Here, we have examined the molecular mechanisms underlying the anti...

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Hlavní autoři: Chou, Ying, Lin, Hui-Chen, Chen, Kuan-Chou, Chang, Chi-Cheng, Lee, Wen-Sen, Juan, Shu-Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724103/
https://ncbi.nlm.nih.gov/pubmed/23424995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12130
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