Estimation of Somatomedin-C Levels in Normals and Patients with Pituitary Disease by Radioimmunoassay

Eitemau Tebyg

• Hormonal Control of Immunoreactive Somatomedin Production by Cultured Human Fibroblasts
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• Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action.
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• Competitive Binding of Somatomedin to the Insulin Receptors of Adipocytes, Chondrocytes, and Liver Membranes
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• Cultured fibroblast monolayers secrete a protein that alters the cellular binding of somatomedin-C/insulinlike growth factor I.
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• Affinity-labeled plasma somatomedin-C/insulinlike growth factor I binding proteins. Evidence of growth hormone dependence and subunit structure.
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