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Transcutaneous delivery of CpG-adjuvanted allergen via laser-generated micropores

BACKGROUND: Two main shortcomings of classical allergen-specific immunotherapy are long treatment duration and low patient compliance. Utilizing the unique immunological features of the skin by transcutaneous application of antigen opens new approaches not only for painless vaccine delivery, but als...

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Detalles Bibliográficos
Main Authors: Hessenberger, Michael, Weiss, Richard, Weinberger, Esther E., Boehler, Christof, Thalhamer, Josef, Scheiblhofer, Sandra
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724055/
https://ncbi.nlm.nih.gov/pubmed/23273971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.09.086
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