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Glycogen Phosphorylase Inhibitor N-(3,5-Dimethyl-Benzoyl)-N’-(β-D-Glucopyranosyl)Urea Improves Glucose Tolerance under Normoglycemic and Diabetic Conditions and Rearranges Hepatic Metabolism

Glycogen phosphorylase (GP) catalyzes the breakdown of glycogen and largely contributes to hepatic glucose production making GP inhibition an attractive target to modulate glucose levels in diabetes. Hereby we present the metabolic effects of a novel, potent, glucose-based GP inhibitor (KB228) teste...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Nagy, Lilla, Docsa, Tibor, Szántó, Magdolna, Brunyánszki, Attila, Hegedűs, Csaba, Márton, Judit, Kónya, Bálint, Virág, László, Somsák, László, Gergely, Pál, Bai, Péter
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723905/
https://ncbi.nlm.nih.gov/pubmed/23936011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069420
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