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Glycogen Phosphorylase Inhibitor N-(3,5-Dimethyl-Benzoyl)-N’-(β-D-Glucopyranosyl)Urea Improves Glucose Tolerance under Normoglycemic and Diabetic Conditions and Rearranges Hepatic Metabolism

Glycogen phosphorylase (GP) catalyzes the breakdown of glycogen and largely contributes to hepatic glucose production making GP inhibition an attractive target to modulate glucose levels in diabetes. Hereby we present the metabolic effects of a novel, potent, glucose-based GP inhibitor (KB228) teste...

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Bibliografiska uppgifter
Huvudupphovsmän: Nagy, Lilla, Docsa, Tibor, Szántó, Magdolna, Brunyánszki, Attila, Hegedűs, Csaba, Márton, Judit, Kónya, Bálint, Virág, László, Somsák, László, Gergely, Pál, Bai, Péter
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723905/
https://ncbi.nlm.nih.gov/pubmed/23936011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069420
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