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Glycogen Phosphorylase Inhibitor N-(3,5-Dimethyl-Benzoyl)-N’-(β-D-Glucopyranosyl)Urea Improves Glucose Tolerance under Normoglycemic and Diabetic Conditions and Rearranges Hepatic Metabolism

Glycogen phosphorylase (GP) catalyzes the breakdown of glycogen and largely contributes to hepatic glucose production making GP inhibition an attractive target to modulate glucose levels in diabetes. Hereby we present the metabolic effects of a novel, potent, glucose-based GP inhibitor (KB228) teste...

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書誌詳細
主要な著者: Nagy, Lilla, Docsa, Tibor, Szántó, Magdolna, Brunyánszki, Attila, Hegedűs, Csaba, Márton, Judit, Kónya, Bálint, Virág, László, Somsák, László, Gergely, Pál, Bai, Péter
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723905/
https://ncbi.nlm.nih.gov/pubmed/23936011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069420
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