Glycogen Phosphorylase Inhibitor N-(3,5-Dimethyl-Benzoyl)-N’-(β-D-Glucopyranosyl)Urea Improves Glucose Tolerance under Normoglycemic and Diabetic Conditions and Rearranges Hepatic Metabolism

Glycogen phosphorylase (GP) catalyzes the breakdown of glycogen and largely contributes to hepatic glucose production making GP inhibition an attractive target to modulate glucose levels in diabetes. Hereby we present the metabolic effects of a novel, potent, glucose-based GP inhibitor (KB228) teste...

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Detalles Bibliográficos
Autores principales: Nagy, Lilla, Docsa, Tibor, Szántó, Magdolna, Brunyánszki, Attila, Hegedűs, Csaba, Márton, Judit, Kónya, Bálint, Virág, László, Somsák, László, Gergely, Pál, Bai, Péter
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723905/
https://ncbi.nlm.nih.gov/pubmed/23936011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069420
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