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Efficient Sampling in Fragment-Based Protein Structure Prediction Using an Estimation of Distribution Algorithm

Fragment assembly is a powerful method of protein structure prediction that builds protein models from a pool of candidate fragments taken from known structures. Stochastic sampling is subsequently used to refine the models. The structures are first represented as coarse-grained models and then as a...

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Detalhes bibliográficos
Main Authors: Simoncini, David, Zhang, Kam Y. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723781/
https://ncbi.nlm.nih.gov/pubmed/23935913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068954
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