VAR2CSA Signatures of High Plasmodium falciparum Parasitemia in the Placenta

Plasmodium falciparum infected erythrocytes (IE) accumulate in the placenta through the interaction between Duffy-binding like (DBL) domains of parasite-encoded ligand VAR2CSA and chondroitin sulphate-A (CSA) receptor. Polymorphisms in these domains, including DBL2X and DBL3X, may affect their antig...

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Main Authors: Rovira-Vallbona, Eduard, Monteiro, Isadora, Bardají, Azucena, Serra-Casas, Elisa, Neafsey, Daniel E., Quelhas, Diana, Valim, Clarissa, Alonso, Pedro, Dobaño, Carlota, Ordi, Jaume, Menéndez, Clara, Mayor, Alfredo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723727/
https://ncbi.nlm.nih.gov/pubmed/23936092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069753
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