S-Nitrosoglutathione Reductase Inhibition Regulates Allergen-Induced Lung Inflammation and Airway Hyperreactivity

Allergic asthma is characterized by Th2 type inflammation, leading to airway hyperresponsivenes, mucus hypersecretion and tissue remodeling. S-Nitrosoglutathione reductase (GSNOR) is an alcohol dehydrogenase involved in the regulation of intracellular levels of S-nitrosothiols. GSNOR activity has be...

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Hlavní autoři: Ferrini, Maria E., Simons, Bryan J., Bassett, David J. P., Bradley, Matthews O., Roberts, Kevan, Jaffar, Zeina
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723687/
https://ncbi.nlm.nih.gov/pubmed/23936192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070351
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