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Role of Reactive Oxygen Species in the Radiation Response of Human Hematopoietic Stem/Progenitor Cells

Hematopoietic stem/progenitor cells (HSPCs), which are present in small numbers in hematopoietic tissues, can differentiate into all hematopoietic lineages and self-renew to maintain their undifferentiated phenotype. HSPCs are extremely sensitive to oxidative stressors such as anti-cancer agents, ra...

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Autors principals: Yamaguchi, Masaru, Kashiwakura, Ikuo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723682/
https://ncbi.nlm.nih.gov/pubmed/23936220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070503
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