Pathoadaptive Mutations in Salmonella enterica Isolated after Serial Passage in Mice

How pathogenic bacteria adapt and evolve in the complex and variable environment of the host remains a largely unresolved question. Here we have used whole genome sequencing of Salmonella enterica serovar Typhimurium LT2 populations serially passaged in mice to identify mutations that adapt bacteria...

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Detalhes bibliográficos
Main Authors: Koskiniemi, Sanna, Gibbons, Henry S., Sandegren, Linus, Anwar, Naeem, Ouellette, Gary, Broomall, Stacey, Karavis, Mark, McGregor, Paul, Liem, Alvin, Fochler, Ed, McNew, Lauren, Rosenzweig, Carolyn Nicole, Rhen, Mikael, Skowronski, Evan W., Andersson, Dan I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723669/
https://ncbi.nlm.nih.gov/pubmed/23936152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070147
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