A possible role for malonyl-CoA in the regulation of hepatic fatty acid oxidation and ketogenesis.

Studied on the oxidation of oleic and octanoic acids to ketone bodies were carried out in homogenates and in mitochondrial fractions of livers taken from fed and fasted rats. Malonyl-CoA inhibited ketogenesis from the former but not from the latter substrate. The site of inhibition appeared to be th...

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Publié dans:	J Clin Invest
Auteurs principaux:	McGarry, J D, Mannaerts, G P, Foster, D W
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1977
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372365/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/874089/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108764
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