Involvement of the Clock Gene Rev-erb alpha in the Regulation of Glucagon Secretion in Pancreatic Alpha-Cells

Disruption of pancreatic clock genes impairs pancreatic beta-cell function, leading to the onset of diabetes. Despite the importance of pancreatic alpha-cells in the regulation of glucose homeostasis and in diabetes pathophysiology, nothing is known about the role of clock genes in these cells. Here...

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Main Authors: Vieira, Elaine, Marroquí, Laura, Figueroa, Ana Lucia C., Merino, Beatriz, Fernandez-Ruiz, Rebeca, Nadal, Angel, Burris, Thomas P., Gomis, Ramon, Quesada, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723646/
https://ncbi.nlm.nih.gov/pubmed/23936124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069939
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