The Salmonella Type III Effector SspH2 Specifically Exploits the NLR Co-chaperone Activity of SGT1 to Subvert Immunity

To further its pathogenesis, S. Typhimurium delivers effector proteins into host cells, including the novel E3 ubiquitin ligase (NEL) effector SspH2. Using model systems in a cross-kingdom approach we gained further insight into the molecular function of this effector. Here, we show that SspH2 modul...

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Main Authors: Bhavsar, Amit P., Brown, Nat F., Stoepel, Jan, Wiermer, Marcel, Martin, Dale D. O., Hsu, Karolynn J., Imami, Koshi, Ross, Colin J., Hayden, Michael R., Foster, Leonard J., Li, Xin, Hieter, Phil, Finlay, B. Brett
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723637/
https://ncbi.nlm.nih.gov/pubmed/23935490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003518
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