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Cell-Cycle Dependence of Transcription Dominates Noise in Gene Expression

The large variability in mRNA and protein levels found from both static and dynamic measurements in single cells has been largely attributed to random periods of transcription, often occurring in bursts. The cell cycle has a pronounced global role in affecting transcriptional and translational outpu...

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Detalhes bibliográficos
Main Authors: Zopf, C. J., Quinn, Katie, Zeidman, Joshua, Maheshri, Narendra
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723585/
https://ncbi.nlm.nih.gov/pubmed/23935476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003161
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