Chikungunya Virus Infection Results in Higher and Persistent Viral Replication in Aged Rhesus Macaques Due to Defects in Anti-Viral Immunity

Chikungunya virus (CHIKV) is a re-emerging mosquito-borne Alphavirus that causes a clinical disease involving fever, myalgia, nausea and rash. The distinguishing feature of CHIKV infection is the severe debilitating poly-arthralgia that may persist for several months after viral clearance. Since its...

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Main Authors: Messaoudi, Ilhem, Vomaske, Jennifer, Totonchy, Thomas, Kreklywich, Craig N., Haberthur, Kristen, Springgay, Laura, Brien, James D., Diamond, Michael S., DeFilippis, Victor R., Streblow, Daniel N.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723534/
https://ncbi.nlm.nih.gov/pubmed/23936572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002343
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