Gene × Physical Activity Interactions in Obesity: Combined Analysis of 111,421 Individuals of European Ancestry

Numerous obesity loci have been identified using genome-wide association studies. A UK study indicated that physical activity may attenuate the cumulative effect of 12 of these loci, but replication studies are lacking. Therefore, we tested whether the aggregate effect of these loci is diminished in...

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主要な著者: Ahmad, Shafqat, Rukh, Gull, Varga, Tibor V., Ali, Ashfaq, Kurbasic, Azra, Shungin, Dmitry, Ericson, Ulrika, Koivula, Robert W., Chu, Audrey Y., Rose, Lynda M., Ganna, Andrea, Qi, Qibin, Stančáková, Alena, Sandholt, Camilla H., Elks, Cathy E., Curhan, Gary, Jensen, Majken K., Tamimi, Rulla M., Allin, Kristine H., Jørgensen, Torben, Brage, Soren, Langenberg, Claudia, Aadahl, Mette, Grarup, Niels, Linneberg, Allan, Paré, Guillaume, Magnusson, Patrik K. E., Pedersen, Nancy L., Boehnke, Michael, Hamsten, Anders, Mohlke, Karen L., Pasquale, Louis T., Pedersen, Oluf, Scott, Robert A., Ridker, Paul M., Ingelsson, Erik, Laakso, Markku, Hansen, Torben, Qi, Lu, Wareham, Nicholas J., Chasman, Daniel I., Hallmans, Göran, Hu, Frank B., Renström, Frida, Orho-Melander, Marju, Franks, Paul W.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723486/
https://ncbi.nlm.nih.gov/pubmed/23935507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003607
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