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Sample size calculation for multicentre efficacy trials of blood-stage malaria antigens

BACKGROUND: Sample size has increasingly become a prerequisite for grant approval. Study size calculations for multicentre trials are more complicated because these sites present different assumptions on incidence of disease expected in the control group; this then changes the mechanism of sample si...

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Detalles Bibliográficos
Autor Principal: Bosomprah, Samuel
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723417/
https://ncbi.nlm.nih.gov/pubmed/23870554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-253
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