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Androgenic Hormones Modulate Autoantibody Responses and Improve Survival in Murine Lupus

Antibodies to native DNA and to polyadenylic acid (Poly A) occur spontaneously and undergo a regulated switch from IgM to IgG during the course of autoimmune disease in NZB/NZW F(1) (B/W) mice. B/W females have higher titers and earlier commitment to 7S antibodies to DNA and Poly A, whereas B/W male...

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Detalhes bibliográficos
Main Authors: Roubinian, Jirayr R., Papoian, Ruben, Talal, Norman
Formato: Artigo
Idioma:Inglês
Publicado em: 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC372318/
https://ncbi.nlm.nih.gov/pubmed/864003
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