C1-inhibitor efficiently inhibits Escherichia coli-induced tissue factor mRNA up-regulation, monocyte tissue factor expression and coagulation activation in human whole blood

Both the complement system and tissue factor (TF), a key initiating component of coagulation, are activated in sepsis, and cross-talk occurs between the complement and coagulation systems. C1-inhibitor (C1-INH) can act as a regulator in both systems. Our aim in this study was to examine this cross-t...

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Detalhes bibliográficos
Main Authors: Landsem, A, Nielsen, E W, Fure, H, Christiansen, D, Ludviksen, J K, Lambris, J D, Østerud, B, Mollnes, T E, Brekke, O-L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722922/
https://ncbi.nlm.nih.gov/pubmed/23607270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12098
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