Inhibition of thyroid-stimulating hormone stimulation of protein kinase, glucose oxidation, and phospholipid synthesis in thyroid slices previously exposed to the hormone.

Prior exposure of thyroid slices to thyrotropin (TSH) induced refractoriness to subsequent stimulation of the cyclic AMP system by the hormone. Although the inhibition is incomplete, we examined whether the reduction in cyclic AMP was sufficient to alter other metabolic effects of TSH. Bovine or dog...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Field, J B, Bloom, G, Chou, C, Kerins, M E
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1977
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372270/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/191470/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108684
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