Liver FOXP3 and PD1/PDL1 Expression is Down-Regulated in Chronic HBV Hepatitis on Maintained Remission Related to the Degree of Inflammation

Background and Aim: T cell expression of PD1 and inhibition of T effector cells by Foxp3(+)-T regulatory cells are among the most powerful mechanisms for achieving a balanced immune response. Our aim was to investigate, how liver FOXP3 and PD1/PDL1 expression is regulated in chronic HBV hepatitis (C...

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Main Authors: Germanidis, Georgios, Argentou, Nikoletta, Hytiroglou, Prodromos, Vassiliadis, Themistoklis, Patsiaoura, Kalliopi, Germenis, Anastasios E., Speletas, Matthaios
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722555/
https://ncbi.nlm.nih.gov/pubmed/23898331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00207
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