Polymorphisms in Drug Metabolism Genes, Smoking, and p53 Mutations in Breast Cancer

Polymorphisms in phase I and phase II enzymes may enhance the occurrence of mutations at critical tumor suppressor genes, such as p53, and increase breast cancer risk by either increasing the activation or detoxification of carcinogens and/or endogenous estrogens. We analyzed polymorphisms in CYP1B1...

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Detalhes bibliográficos
Main Authors: Van Emburgh, Beth O., Hu, Jennifer J., Levine, Edward A., Mosley, Libyadda J., Case, L. Douglas, Lin, Hui-Yi, Knight, Sommer N., Perrier, Nancy D., Rubin, Peter, Sherrill, Gary B., Shaw, Cindy S., Carey, Lisa A., Sawyer, Lynda R., Allen, Glenn O., Milikowski, Clara, Willingham, Mark C., Miller, Mark Steven
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722359/
https://ncbi.nlm.nih.gov/pubmed/17683074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20365
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